The Purpose of the Study Was to Determine the Effect of Endurance Training at Moderate and Low Altitude on Selected Hematological Variables. For This Purpose 12 Runner from Sports Hostel Pithoragarh Which Is Situated at Moderate Altitude (Above 1500 Meter) and 12 Runners from Sports Hostel Dehradun Which Is Situated at Low Altitude (Below 600 Meter), Age Ranging Between (14 to 17) Were Purposively Selected. Participants Were Tested on the Selected Hematological Variables I.E. Hemoglobin and Rbc. to Assess the Effect of Endurance Training, All the Selected Subjects from Both the Altitude Participated In 12 Weeks of Training Programme at Their Respective Place. the Testing of Hematological Variables Was Carried Out In a Pathology Laboratory. the Data Was Tested By Applying the Analysis of Covariance and Level of Significance Was Set at 0.05. the Result of the Study Indicated That the Training Program Is Having a Positive Influence at Both the Altitude and There Is a Significant Improvement on Hemoglobin and Rbc Level at Moderate Altitude Training Group As Compared to the Low Altitude Training Group In Terms of the Mean Values.