Alternate Synthetic Approaches to Ziprasidone, Preparation and Characterization of Its Related Compounds

Published in Journal

Journal of Advances in Science and Technology [JAST] (Vol:4/ Issue: 8) DOI: 10.29070/JAST
Authors: Shirodkar Ganpat Mahadeo,
Subjects: Science & Technology

Year: Feb, 2013
Volume: 4 / Issue: 8
Pages: 0 - 0 (0)
Publisher: Ignited Minds Journals
Source:
E-ISSN: 2230-9659
DOI:
Published URL: http://ignited.in/a/1740
Published On: Feb, 2013

Article Details

Alternate Synthetic Approaches to Ziprasidone, Preparation and Characterization of Its Related Compounds |

Shirodkar Ganpat Mahadeo, in Journal of Advances in Science and Technology | Science & Technology

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ABSTRACT:

Aseries of substituted piperazine derivatives have been synthesized and testedfor antibacterial activity. The antibacterial activity was tested againstGram-positive and Gram-negative bacteria strains like B. subtilis, B. pumillis, E. coli, and P. aeruginosa. These entire compounds have been characterized bytheir IR and 1H NMR spectral data. All synthesized compounds showed significantactivity against bacterial strains. The biological screening showed that thecompounds Vc, Vd and Ve are the most active ones showing an interestingantibacterial activity.