Antidiarrhoeal Activity of Aqueous Leaf Extract of Momordica Spp. (Cucurbitaceae)

Published in Journal

Journal of Advances and Scholarly Researches in Allied Education [JASRAE] (Vol:20/ Issue: 2) DOI: 10.29070/JASRAE
Authors: Shikha Kumari*, Shane Meraj Sajja, Puspaa Sinha,
Subjects: Multidisciplinary Academic Research

Year: Apr, 2023
Volume: 20 / Issue: 2
Pages: 473 - 475 (3)
Publisher: Ignited Minds Journals
Source:
E-ISSN: 2230-7540
DOI:
Published URL: http://ignited.in/p/307295
Published On: Apr, 2023

Article Details

Antidiarrhoeal Activity of Aqueous Leaf Extract of Momordica Spp. (CUCURBITACEAE) | Original Article

Shikha Kumari*, Shane Meraj Sajja, Puspaa Sinha, in Journal of Advances and Scholarly Researches in Allied Education | Multidisciplinary Academic Research

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ABSTRACT:

Antidiarrhoeal activity of aqueous leaf extract of Momordica charantia (CUCURBITACEAE) was evaluated on castor oil induced diarrhea, gastro-intestinal transit, intestinal fluid accumulation and gastric emptying in mice. The aqueous extract of its leaves showed inhibitory activity against castor oil induced diarrhoea. Inhibition of the gastrointestinal population and fluid secretion by the extract suggest that the existing extract exert the anti-diarrhoeal activity by anti-secretory mechanism.