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DOI: https://doi.org/10.29070/8swg8r07
The Role of MRI in Breast Biopsy: A Comprehensive Analysis of Diagnostic Accuracy, Techniques, and Clinical Outcomes
radu23k@gmail.com ,
Abstract: Breast cancer remains one of the most prevalent malignancies affecting women worldwide. Magnetic Resonance Imaging (MRI) has emerged as a pivotal tool in the diagnostic workup of breast lesions, particularly in cases where mammography and ultrasound yield inconclusive results. This paper aims to provide a detailed analysis of the role of MRI in breast biopsy, focusing on its diagnostic accuracy, various techniques employed, and the clinical outcomes associated with its use. We present expanded tables summarizing key findings from recent studies, highlighting the advantages and limitations of MRI-guided breast biopsy.
Keywords: Breast biopsy, MRI-guided biopsy, Breast cancer diagnosis, Magnetic Resonance Imaging (MRI), Vacuum-assisted biopsy (VAB), Core needle biopsy (CNB), Diagnostic accuracy, Sensitivity and specificity, False-negative rate, Dense breast tissue, Multicentric breast lesions, Post-neoadjuvant therapy, Wire localization, Image-guided biopsy, Breast lesion characterization, High-risk breast cancer, Clinical outcomes, Complication rates, Patient satisfaction, Breast imaging reporting and data system (BI-RADS)
INTRODUCTION
Breast biopsy is a critical step in the diagnosis of breast cancer, providing definitive histological confirmation of suspicious lesions. While mammography and ultrasound are commonly used for initial imaging, MRI offers superior soft tissue contrast and is particularly useful in evaluating dense breast tissue, multifocal or multicentric disease, and assessing the extent of disease. This paper reviews the current literature on MRI-guided breast biopsy, with an emphasis on its diagnostic accuracy, techniques, and clinical outcomes.
METHODS
A comprehensive literature search was conducted using PubMed, Embase, and Cochrane Library databases. Studies published between 2010 and 2023 that evaluated the use of MRI in breast biopsy were included. Data on diagnostic accuracy, techniques, and clinical outcomes were extracted and summarized in expanded tables.
RESULTS
Table 1: Diagnostic Accuracy of MRI-Guided Breast Biopsy
Table 2: Techniques Used in MRI-Guided Breast Biopsy
Table 3: Clinical Outcomes of MRI-Guided Breast Biopsy
DISCUSSION
MRI-guided breast biopsy has demonstrated high diagnostic accuracy, particularly in challenging cases such as dense breast tissue and multicentric lesions. The technique offers several advantages, including superior soft tissue contrast and the ability to guide biopsies in real-time. However, it is not without limitations, including the need for specialized equipment and the potential for false negatives. The clinical outcomes are generally favorable, with low complication rates and high patient satisfaction.
CONCLUSION
MRI-guided breast biopsy is a valuable tool in the diagnostic armamentarium for breast cancer. Its high diagnostic accuracy, coupled with favorable clinical outcomes, makes it an essential technique for evaluating complex breast lesions. Future research should focus on optimizing techniques and reducing limitations to further enhance its utility in clinical practice.