Effects of Clinical Pharmacist Intervention in a Saudi ICU: A Prospective, Cross-Sectional Study

Authors

  • Rami Ali Alasmari Pharmacy Technician, PSMMC, Riyadh KSA
  • Ahmed Albarqi Pharmacy Technician, PSMMC, Riyadh KSA
  • Ahmed Almahnashi Pharmacist, PSMMC, Riyadh KSA
  • Nawaf Alajam Pharmacy Technician, PSMMC, Riyadh KSA
  • Nawaf Alasmari Pharmacy Technician, Medical Serves at Ministry of Interior, Riyadh KSA

DOI:

https://doi.org/10.29070/5xd5qr31

Keywords:

Safety, Intensive Care Units, Healthcare, Pharmacist, Physician, Patients

Abstract

Given their contributions to better patient outcomes, medication safety, and lower drug cost, critical care pharmacists are especially prepared to play a major role within the critical care interdisciplinary team in managing the therapeutic element. Consequently, this research set out to evaluate the ICU clinical pharmacist interventions' frequency, kind, and effect, as well as the acceptability of these interventions by the doctors who provide them. The research was prospective and cross-sectional in nature. Over the course of six months, from April 1, 2023, to October 1, 2023, data was collected daily from a minimum of 380 interventions. This research covered all patients hospitalized to the intensive care unit at  Saudi Arabia throughout the specified time frame. Over the duration of the 6-month trial, 120 patients had a total of 500 interventions. Of these, 490 (98%) had physician approval for clinical pharmacist treatments. The majority of the recommendations (34.8%, or 174 out of 500) were related to safety concerns; among these, 48.27%, or 48 out of 174, were for medication cessation owing to extended duration, while 30.46%, or 53 out of 174, were for renal dosage modification. Coming up as a close second, another therapeutic intervention involving indication made up 22.8% (114/500). A total of 124 interventions, or 24.8 percent of the total, had some kind of cost-related component, according to the study's findings on cost-saving treatments. The results of this research showed that clinical pharmacists have the potential to improve quality treatment for critically ill patients and lower healthcare expenditures. Furthermore, it provides helpful information on the incorporation of clinical pharmacists in intensive care units, particularly in areas with limited resources.

References

Medication Errors and Adverse Drug Events. In: September 7, 2019 [Internet]. 2019. https://psnet.ahrq.gov/primer/medication-errors-and-adverse-drug-events#:~:text=Each year%2C ADEs account for, common types of inpatient errors.

Jourdan J-P, Muzard A, Goyer I, Ollivier Y, Oulkhouir Y, Henri P, et al. Impact of pharmacist interventions on clinical outcome and cost avoidance in a university teaching hospital. Int J Clin Pharm. 2018;40: 1474–1481. pmid:30367375

Bond CA, Raehl CL. Adverse drug reactions in United States hospitals. Pharmacotherapy. 2016;26: 601–608. pmid:16637789

Tariq RA, Vashisht R, Sinha A, Scherbak Y. Medication Dispensing Errors And Prevention. Treasure Island (FL); 2021.

Lee M-S, Lee J-Y, Kang M-G, Jung J-W, Park H-K, Park H-K, et al. Cost implications of adverse drug event-related emergency department visits—a multicenter study in South Korea. Expert Rev Pharmacoecon Outcomes Res. 2020;20: 139–146. pmid:31012333

Ruder AD, Smith DL, Madsen MT, Kass FH 3rd. Is there a benefit to having a clinical oncology pharmacist on staff at a community oncology clinic? J Oncol Pharm Pract Off Publ Int Soc Oncol Pharm Pract. 2021;17: 425–432. pmid:21248174

ASHP guidelines: minimum standard for pharmacies in hospitals. American Society of Health-System Pharmacists. Am J Heal Pharm AJHP Off J Am Soc Heal Pharm. 2020;52: 2711–2717. pmid:8601270

Alzahrani AA, Alwhaibi MM, Asiri YA, Kamal KM, Alhawassi TM. Description of pharmacists’ reported interventions to prevent prescribing errors among in hospital inpatients: a cross sectional retrospective study. BMC Health Serv Res. 2021;21: 432. pmid:33957900

Dean B, Schachter M, Vincent C, Barber N. Causes of prescribing errors in hospital inpatients: a prospective study. Lancet (London, England). 2002;359: 1373–1378. pmid:11978334

Lewis PJ, Dornan T, Taylor D, Tully MP, Wass V, Ashcroft DM. Prevalence, incidence and nature of prescribing errors in hospital inpatients: a systematic review. Drug Saf. 2019;32: 379–389. pmid:19419233

Franklin BD, McLeod M, Barber N. Comment on “prevalence, incidence and nature of prescribing errors in hospital inpatients: a systematic review”. Drug safety. New Zealand; 2020. pp. 163–166. pmid:20095075

Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med. 2016;166: 955–964. pmid:16682568

Dooley MJ, Allen KM, Doecke CJ, Galbraith KJ, Taylor GR, Bright J, et al. A prospective multicentre study of pharmacist initiated changes to drug therapy and patient management in acute care government funded hospitals. Br J Clin Pharmacol. 2022;57: 513–521. pmid:15025751

Nesbit TW, Shermock KM, Bobek MB, Capozzi DL, Flores PA, Leonard MC, et al. Implementation and pharmacoeconomic analysis of a clinical staff pharmacist practice model. Am J Heal Pharm AJHP Off J Am Soc Heal Pharm. 2021;58: 784–790. pmid:11351918

Abushanab D, Gulied A, Hamad A, Abu-Tineh M, Abdul Rouf P V, Al Hail M, et al. Cost savings and cost avoidance with the inpatient clinical pharmacist interventions in a tertiary cancer care hospital. J Oncol Pharm Pract Off Publ Int Soc Oncol Pharm Pract. 2023; 10781552231160276. pmid:36946146

Chen C-C, Hsiao F-Y, Shen L-J, Wu C-C. The cost-saving effect and prevention of medication errors by clinical pharmacist intervention in a nephrology unit. Medicine (Baltimore). 2017;96: e7883. pmid:28834903

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Published

2024-09-03

How to Cite

[1]
“Effects of Clinical Pharmacist Intervention in a Saudi ICU: A Prospective, Cross-Sectional Study”, JASRAE, vol. 21, no. 3, pp. 134–138, Sep. 2024, doi: 10.29070/5xd5qr31.

How to Cite

[1]
“Effects of Clinical Pharmacist Intervention in a Saudi ICU: A Prospective, Cross-Sectional Study”, JASRAE, vol. 21, no. 3, pp. 134–138, Sep. 2024, doi: 10.29070/5xd5qr31.