Phytochemical analysis and Antioxidant activity of Medicinal Plants used in Traditional Medicine for Diabetes Management

Abstract

The accumulation of harmful free radicals, which may be compared to oxidative stress, is a major contributor to several illnesses and a major concern for public health. The second kind of diabetes falls under this category. Cardiovascular problems account for 75% of diabetes fatalities in the Central African Republic, where an estimated 60,000 people have the disease. An alternative to synthetic antidiabetics is available in the traditional African pharmacopoeia. The first time, through cotton. The second time, using 3 mm wattman paper. Lastly, the filtrates are evaporated using a rotary evaporator. With this powder in hand, we were able to conduct experiments with phytochemicals and antioxidants. Following the sorting of phytochemicals, DPPH was used to evaluate the antiradical activity, and the ferric thiocyanate procedure was used to test the suppression of lipid peroxidation. Sterols, polyterpenes, polyphenols, flavonoids, and saponins were identified by phytochemical sorting as being present in these plants. It has been shown using thin-layer chromatography for methanol extracts that Millettia laurentii includes a reasonably high amount of polyphenols, however the concentration of sterols and polyterpenes is greater in the ethanol extract. In contrast, Khaya anthotheca and Desmodium tortuosum, which are rich in flavonoids and polyphenols, respectively, have antioxidant and antiradical important activity at 10.4 ± 0.3 and 9.5 ± 0.7, respectively.