Development of Novel Drug Delivery Systems for Enhancing the Bioavailability of Poorly Soluble Drugs
DOI:
https://doi.org/10.29070/whqd0t85Keywords:
Bioavailability, Solubilization, chemical modifications, Novel Drug Delivery Systems, SolubilityAbstract
One of the most effective ways to solve issues with medication bioavailability is via the use of novel drug delivery systems (NDDS). It refers to how quickly and to what degree a medicine reaches its intended target following delivery. Since only a tiny percentage of the dose actually makes it into the bloodstream and reaches the intended target, most modern medications have low bioavailability and need greater dosages. A large quantity of medication is wasted and unwanted side effects occur as a consequence of this. The primary goal of pharmaceutical technology is to increase the bioavailability of medications by making them more soluble and permeable. The idea behind NDDS is nanotechnology, which allows for the decrease in medication particle weight while simultaneously increasing stability and enhancing functioning. This review looks at the many methods for increasing bioavailability and the pros and cons of each.
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