Efficacy of Non Invasive Ventilation Techniques in Acute Respiratory Failure
DOI:
https://doi.org/10.29070/ky6a7129Keywords:
Acute respiratory failure (ARF), acute exacerbation of COPD (AECOPD), non-invasive positive pressure ventilation (NIPPV), non-invasive ventilation (NIV)Abstract
One of the leading causes of hospitalization, illness, and mortality globally is acute respiratory failure (ARF). One of the major causes of chronic obstructive pulmonary disease (COPD) is acute exacerbations, which provide a significant barrier to therapy. Improving patient outcomes while reducing the need for intrusive mechanical breathing requires effective management methods, such as non-invasive ventilation (NIV). The purpose of this research was to compare the effectiveness of conventional treatment for ARF caused by AECOPD with that of non-invasive ventilation administered via a portable device. Seventy patients hospitalized to Saudi Arabia's Buraidah Central Hospital with ARF as a result of AECOPD were the subjects of a prospective cohort research. One group of patients received standard treatment, whereas the other group received NIPPV, or non-invasive positive pressure breathing. While mortality rate, co-morbidities, length of stay in the intensive care unit, and longevity of NIV usage were secondary objectives, NIPPV failure was the major result. The patients' average age was 61.08, and 86% of them were men. The success rate of the NIPPV group was 74%, which was significantly greater than the conventional treatment group's rate of 54%. The leading cause of NIPPV failure was deteriorating arterial blood gases (33%), whereas the most common consequence was face skin abrasion (17%). Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients who are experiencing acute respiratory failure may benefit from NIV as a first-line treatment. It is already an essential part of ARF therapy, and its link to reduced mortality, fewer intubation rates, and quicker acidosis correction just adds to that.
References
Antonelli, M., Conti, G., & Moro, M. L. (2020). Noninvasive ventilation for treatment of acute respiratory failure. New England Journal of Medicine, 343(7), 468–473.
Keenan, S. P., Sinuff, T., Burns, K. E., Muscedere, J., Kutsogiannis, J., Mehta, S., & Cook, D. J. (2011). Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting. Canadian Medical Association Journal, 183(3), E195–E214.
Rochwerg, B., Brochard, L., Elliott, M. W., Hess, D., Hill, N. S., Nava, S., & Antonelli, M. (2017). Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. European Respiratory Journal, 50(2), 1602426
Osadnik, C. R., Tee, V. S., Carson-Chahhoud, K. V., Picot, J., Wedzicha, J. A., & Smith, B. J. (2017). Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews, 7(7), CD004104.
Ferreyro, B. L., Angriman, F., Munshi, L., Del Sorbo, L., Ferguson, N. D., Rochwerg, B., & Brochard, L. J. (2020). Association of noninvasive oxygenation strategies with all-cause mortality in adults with acute hypoxemic respiratory failure. JAMA, 324(1), 57–67.
Al Ghobain, M., Al-Hajjaj, M. S., & Wali, S. O. (2011). Prevalence of chronic obstructive pulmonary disease among smokers attending primary healthcare clinics in Saudi Arabia. Saudi Medical Journal, 32(8), 827–833.
Sergeant E (2018): Epitools epidemiological calculators. Ausvet Pty Ltd.
Mirabile V, Shebl E, Sankari A et al. (2024): Respiratory Failure in Adults. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC
Doshi P, Whittle J, Bublewicz M et al. (2018): HighVelocity Nasal Insufflation in the Treatment of Respiratory Failure: A Randomized Clinical Trial. Ann Emerg Med., 72:73-83.
Miyazaki Y, Inoue S, Hirose H et al. (2021): HighVelocity Nasal Insufflation Increases Nasopharyngeal Pressure with Flow-Dependent Manner Compared with High Flow Nasal Cannula in Adult Volunteers - A SingleCenter Prospective Observational Study. Kobe J Med Sc., 67:92-7.
Schmitt F, Gruneberg D, Schneider N et al. (2022): Non-Invasive Ventilation as a Therapy Option for Acute Exacerbations of Chronic Obstructive Pulmonary Disease and Acute Cardiopulmonary Oedema in Emergency Medical Services. J Clin Med., 11:325-41.
Barnes P (2016): Sex Differences in Chronic Obstructive Pulmonary Disease Mechanisms. Am J Respir Crit Care Med., 193:813-4.
Patel A, Patel A, Singh S et al. (2019): Global initiative for chronic obstructive lung disease: the changes made. Cureus, 11:68-74.
Jarad N (2011): Chronic obstructive pulmonary disease (COPD) and old age? Chron Respir Dis., 8:143-51.
Phua J, Kong K, Lee K et al. (2005): Noninvasive ventilation in hypercapnic acute respiratory failure due to chronic obstructive pulmonary disease vs. other conditions: effectiveness and predictors of failure. Intensive Care Med., 31:533-9.
Liu L, Qiu H, Zheng R et al. (2005): Prospective randomized controlled clinical study of early use of noninvasive positive pressure ventilation in the treatment for acute exacerbation of chronic obstructive pulmonary disease. https://pubmed.ncbi.nlm.nih.gov/16105426/
Brochard L, Mancebo J, Wysocki M et al. (1996): Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med., 333:817-22.
Wedzicha J (1996): Non-invasive ventilation for exacerbations of respiratory failure in chronic obstructive pulmonary disease. Thorax, 51:35-47.
Doshi P, Whittle J, Dungan G et al. (2020): The ventilatory effect of high velocity nasal insufflation compared to non-invasive positive-pressure ventilation in the treatment of hypercapneic respiratory failure: A subgroup analysis. Heart Lung, 49:610-5.
Golmohamad A, Johnston R, Hay K et al. (2022): Safety and efficacy of high-flow nasal cannula therapy in acute hypercapnic respiratory failure: a retrospective audit. Intern Med J., 52:259-64.
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