Effect of Standardized IV Compounding Protocols on Patient Safety Outcomes
DOI:
https://doi.org/10.29070/1vqg4406Keywords:
IV room, sterile compounding, patient safety, USP <797>, medication errors, standardized protocolsAbstract
Intravenous (IV) medications are classified as high-risk therapies due to their direct entry into the systemic circulation and limited opportunity for error correction. Errors during IV compounding may result in severe adverse drug events, infections, increased healthcare costs, and patient morbidity. This study examines the effect of implementing standardized IV compounding protocols on patient safety outcomes in hospital pharmacy IV rooms. A structured review of international guidelines and published studies was conducted, complemented by analysis of reported safety indicators such as medication errors, contamination rates, and adverse drug events. Findings demonstrate that standardized protocols significantly reduce compounding errors, improve aseptic compliance, and enhance overall patient safety. The study highlights the importance of protocol-driven IV room practices aligned with USP <797>, ISMP, ASHP, and accreditation standards.
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References
1. United States Pharmacopeia. USP <797> Pharmaceutical Compounding—Sterile Preparations.
2. Institute for Safe Medication Practices (ISMP). Guidelines for Safe Preparation of Compounded Sterile Preparations.
3. American Society of Health-System Pharmacists (ASHP). Guidelines on Compounding Sterile Preparations.
4. Cousins DH et al. Medication errors in intravenous drug preparation. Qual Saf Health Care.
5. Hedlund N et al. Impact of standardized compounding on patient safety. Eur J Hosp Pharm.
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