Recurrent Pregnancy Loss: A Study on Its Etiological Factors, Endoglin Gene’s Impact and Genetic Polymorphisms

Understanding and Treating Recurrent Pregnancy Loss

Abstract

Recurrent pregnancy loss is a significant conceptive medical problem, influencing 2–5 of couples. Basic built up causes incorporate uterine irregularities, antiphospholipid syndrome, hormonal and metabolic issues, and cytogenetic variations from the norm. However, different etiologies have been proposed as yet thought to be disputable, for example, incessant endometritis, acquired thrombophilias, luteal stage insufficiency, and high sperm DNA fracture levels. Throughout the years, proof-based medicines, for example, careful adjustment of uterine abnormalities or anti-inflammatory medication and heparin for antiphospholipid syndrome, have improved couples with recurrent pregnancy loss. Be that as it may, practically 50 of the cases stay unexplained and are exactly treated utilizing progesterone supplementation, anticoagulation, as well as immunomodulatory medicines.