A Study on the Biological Evaluation of Dihydropyridines
Effects of newly synthesised compounds on blood pressure in male rats
Keywords:
biological evaluation, dihydropyridines, substituting, analogues, nifedipine, calcium channel blocker, synthesised compounds, blood pressure, male rats, tail-cuff procedureAbstract
By substituting 1-(4-Nitrobenzyl)-5-imidazolyl or 2-methylthio-1-(4-Nitrobenzyl)-5-imidazolyl for the orthonitrophenyl group on location 4, new analogues of nifedipine, an established calcium channel blocker, were synthesised. In male rats, the effects of the newly synthesised compounds on blood pressure were analysed using an indirect tail-cuff procedure at 15, 30, and 60 minutes after administration and compared to nifedipine.Published
2021-04-01
How to Cite
[1]
“A Study on the Biological Evaluation of Dihydropyridines: Effects of newly synthesised compounds on blood pressure in male rats”, JASRAE, vol. 18, no. 3, pp. 33–38, Apr. 2021, Accessed: Sep. 20, 2024. [Online]. Available: https://ignited.in/index.php/jasrae/article/view/13079
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Section
Articles
How to Cite
[1]
“A Study on the Biological Evaluation of Dihydropyridines: Effects of newly synthesised compounds on blood pressure in male rats”, JASRAE, vol. 18, no. 3, pp. 33–38, Apr. 2021, Accessed: Sep. 20, 2024. [Online]. Available: https://ignited.in/index.php/jasrae/article/view/13079