Synthesis of 4-Thiazolidinone Derivatives

Synthesis and Antimicrobial Activity of 4-Thiazolidinone Derivatives

Abstract

The amalgamation of 2-acetyl-subbed 1-naphthol was first acted within the sight of icy acidic corrosive and zinc chloride by the acetylation of subbed 1-napthol. This compound on treatment with KCNS and Br2 yielded 2-(2-amino-1,3-thiazol-4-yl)- supplanted naphthalen-1-ol which gave Schiff Bases on simple buildup with sweet-smelling aldehyde. This give 4-thiazolidinone subsidiaries on the cyclo-buildup response with mercaptoacetic corrosive. The combined mixes were depicted by spectroscopy of the essential examination, 1 H NMR, IR. They have investigated newly combined mixes for their antimicrobial exercises.