Biological Activity of Quinazoline and Their Fused-Ring Systems

Synthesis and Characterization of Quinazoline-2-thiols as Potential Vulcanization Accelerators

Authors

  • Ravish Kumar Chauhan Author

Keywords:

Quinazoline, fused-ring systems, biological activity, heterocyclic thiols, vulcanization accelerators, derivatives, condensation, isothiocyanato, substituted phenyl methyl, dihydronaphthalene, primary aromatic amines, elemental analysis, IR spectroscopy, mass spectroscopy

Abstract

Quinazoline and their fused-ringsystems are well known for their potential biological activity. Inspired bythis and in view of the usefulness of heterocyclic thiols as vulcanizationaccelerators, new derivatives viz. Quinazoline-2-thiols were prepared.These  were synthesized by the condensation  of 2-[isothiocyanato(substituted phenyl)methyl]-3,4-dihydronaphthalene-1(2H)-one with primaryaromatic  amines. All the preparedcompounds have been characterized by elemental analysis, IR and mass spectroscopy.

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Published

2012-02-01

Issue

Vol. 3 No. 4 (2012): Journal of Advances in Science and Technology (JAST)

Section

Articles