Effect of Biological Studies of Various New Substituted Phenyl Pyrazol Pyridin-2-Amine Derivatives

Synthesis, Spectral Analysis, and Biological Activities of New Substituted Phenyl Pyrazol Pyridin-2-Amine Derivatives

Abstract

A new series of 2-chlorobenzaldehyde N-ethyl pyridin-2-amine (2a-2e), 1-(5-(2-substitutedphenyl)-3-(pyridin-2-ylamino)-4,5-dihydro-1H-pyrzol-1-yl)ethanone (3a-3e). 2,3-dibromo-3-(2- substitutedphenyl)-N-(pyridin-2-yl)propanamide (4a-4e) & N-(5-(2-substitutedphenyl)-1-phenyl-1H-pyrazol-3-yl)pyridin-2-amine (5a-5e) were prepared in present study. The structure of allthese newly synthesized compounds was confirmed on the basis of spectral (IR, 1HNMRand mass) and analytical data. Compound 5b was found to be the most potentcompound of the present study. It exhibited better insecticidal and antifungalactivities than the standards parathion and fluconazole, respectively,