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Authors

Manisha Thakur

Dr. Anita Chauhan

Abstract

A complex neurodevelopmental disorder known as autism spectrum disorder (ASD) is characterized by difficulties with behavior, socialization, and communication. ASD has a complex etiology, with environmental and genetic variables playing a role in its development. The purpose of this research is to assess our current knowledge of the genetic predispositions and environmental exposures that raise a child's risk of autism spectrum disorder (ASD). To find important risk variables, we examined data from several epidemiological studies, genome-wide association studies (GWAS), and environmental health studies. Our results demonstrate the significant contribution that genetic mutations both inherited and de novo make to the increased risk of ASD. Critical environmental factors that we also discovered were maternal illnesses, prenatal pollution exposure, and dietary deficits. This integrated method emphasizes how important it is to take into account both environmental and genetic elements in order to better understand and maybe lower the risk of ASD.

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