Evaluation of Antibacterial Activity of Various Sample Extracts Against Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella typhi

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Published: Mar 1, 2024
DOI: https://doi.org/10.29070/ny0x7910
Keywords:
Antibacterial activity, medicinal plants, phytochemicals, pharmacological potential, antioxidant activity, traditional medicine, drug discovery

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Authors

Arti Soni

Research Scholar, Shri Krishna University, Chhatarpur, M.P.

Dr. Suryakant

Assistant Professor, Shri Krishna University, Chhatarpur, M.P.

Abstract

This study investigates the antibacterial potential of medicinal plant extracts from the Sagar district of Madhya Pradesh, India. Bark, stem, root, and leaf samples were collected seasonally and processed using the Soxhlet extraction method with 80% methanol. The antibacterial activity of the extracts was evaluated against Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella typhi using the agar well diffusion method. Qualitative phytochemical screening identified alkaloids, flavones, phenols, saponins, terpenoids, tannins, and other bioactive compounds. Quantitative analysis using the Folin-Denis method revealed significant polyphenol content, indicative of potential antioxidant activity. The extracts demonstrated variable antibacterial efficacy, with notable inhibition zones against Staphylococcus aureus and Bacillus subtilis. These findings underscore the pharmacological potential of the plant extracts, supporting their traditional medicinal use and highlighting their relevance for modern pharmaceutical applications. Further exploration of their therapeutic properties and mechanisms of action is essential to unlock their full potential in drug development.

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Article Details

Issue

Vol. 21 No. 1 (2024): Journal of Advances in Science and Technology (JAST)

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