New Perspectives on the Nanogel Drug Delivery System Based on Nanoparticles

Advances and Applications in Nanogel Drug Delivery Systems

Abstract

Nanogels (nanoparticles made of a hydrogel) are nanoscale networks of deliquescent oramphiphilic chemical chains that are swelled and filled with nanomaterials. Drug–polymer interactionsand the development of cutting-edge 3D networks may play a role in this. Nanogels can be preparedusing a wide variety of methods, including particle gelation, inverse mini emulsion, dispersion, chemicalcross linking, biopolymer manufacturing, and so on. Methods for determining its properties includescanning electron microscopy, differential scanning calorimetry, Fourier transform infraredspectroscopy, drug content, particle size, zeta potential, and pharmacological efficacy. In addition, it canbe tested using in vitro drug release as well as in vivo testing using appropriate animal modelling. Thisoverview article focuses on the fundamental approach of nanogels, assessment terminology, theirapplication in industry, and future research prospects.