The Role of Sambucus nigra Extracts in Animal Models of High Blood Pressure
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Keywords:
Sambucus nigra extracts, animal models, high blood pressure, natural polyphenols, oxidative stress, arterial hypertension, antioxidant, biochemical markers, histological changes, glutathione-peroxidase, superoxide-dismutase, nutritional supplement, chronic cardiovascular illnesses, metabolic illnesses, endothelial cellsAbstract
Natural polyphenols are well-known to have the chemical and physical qualities that helpprotect vital biomolecules including lipids, proteins, and nucleic acids against oxidation. Specificenzymatic measurements and non-specific indicators were used to assess the level of oxidative stress inexperimentally produced arterial hypertension by the administration of L-NAME. Results demonstratedthe antioxidant and protective effect of Sambucus nigra extract on biochemical markers and histologicalchanges in experimental arterial hypertension. Glutathione-peroxidase and superoxide-dismutaseactivities are markedly reduced in the hypertension group compared to the polyphenol-protected group.The polyphenolic extract of Sambucus nigra may be useful as a nutritional supplement in chroniccardiovascular and metabolic illnesses if its effects on the functionality of endothelial cells, such asmembrane sensitivity and intracellular signalling, are understood.Published
2022-07-01
How to Cite
[1]
“The Role of Sambucus nigra Extracts in Animal Models of High Blood Pressure: -”, JASRAE, vol. 19, no. 4, pp. 400–403, Jul. 2022, Accessed: Jul. 03, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/13980
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Section
Articles
How to Cite
[1]
“The Role of Sambucus nigra Extracts in Animal Models of High Blood Pressure: -”, JASRAE, vol. 19, no. 4, pp. 400–403, Jul. 2022, Accessed: Jul. 03, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/13980