Synthesis Characterization Biological Activity of Heterocyclic Compounds

Synthesis, Characterization, and Biological Activity of Heterocyclic Compounds

Authors

  • Anil Wamanrao Vadal
  • Dr. Renu Saxena

Keywords:

Schiff bases, malonic acid di hydrazide, 1,2,4-triazole, substituted benzaldehydes, thiazolidines, thioglycolic acid, glycine, FT-IR, 1 H-NMR, Uvvis spectra, melting temperatures, T.L.C. purity, antibacterial activity

Abstract

To get Schiff bases derivatives malonic acid di hydrazide was reacted with CS2 KOH, followedby hydrazine hydrate. This produced 1,2,4-triazole, which was then reacted with various substitutedbenzaldehydes. Thiazolidines were produced via the reaction of Schiff bases with thioglycolic acid. Asimilar reaction between Schiff bases and glycine yielded imidazolidinone. FT-IR, 1 H-NMR, Uvvis spectra,melting temperatures, and T.L.C. purity checks were used to describe the compounds. Antibacterialactivity was tested on a subset of the produced compounds.

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Published

2022-12-01

How to Cite

[1]
“Synthesis Characterization Biological Activity of Heterocyclic Compounds: Synthesis, Characterization, and Biological Activity of Heterocyclic Compounds”, JASRAE, vol. 19, no. 6, pp. 540–545, Dec. 2022, Accessed: Jul. 01, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/14219

Issue

Vol. 19 No. 6 (2022): Journal of Advances and Scholarly Researches in Allied Education (JASRAE)

Section

Articles

How to Cite

[1]
“Synthesis Characterization Biological Activity of Heterocyclic Compounds: Synthesis, Characterization, and Biological Activity of Heterocyclic Compounds”, JASRAE, vol. 19, no. 6, pp. 540–545, Dec. 2022, Accessed: Jul. 01, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/14219