Strategies for Solution NMR Studies of Macromolecular Assemblies
Advancements in Solution NMR Techniques for Macromolecular Studies
Keywords:
solution NMR, macromolecular assemblies, TROSY, isotope labeling techniques, NMR instrumentation, biological macromolecules, high-resolution NMR, layer proteins, monomeric proteins, intermolecular interactionsAbstract
Transverse relaxation-optimized spectroscopy (TROSY), in mix with isotope labeling techniques and with upgrades in NMR instrumentation, have extraordinarily stretched out applications of NMR spectroscopy to substantial biological macromolecules that were generally not open to high-goals arrangement state NMR. Critical ongoing applications of TROSY incorporate the structure judgments of vital layer proteins in cleanser micelles, basic and functional studies of vast proteins in monomeric frame and in macromolecular buildings, and examinations of intermolecular associations in huge edifices. In addition, TROSY can enhance measurements of NMR parameters, for example, leftover dipolar couplings and scalar couplings crosswise over hydrogen bonds, which add to a further enhancement of the quality and the exactness of arrangement structures of substantial proteins and oligonucleotides.Published
2018-10-01
How to Cite
[1]
“Strategies for Solution NMR Studies of Macromolecular Assemblies: Advancements in Solution NMR Techniques for Macromolecular Studies”, JASRAE, vol. 15, no. 9, pp. 274–278, Oct. 2018, Accessed: Jul. 08, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/8845
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Articles
How to Cite
[1]
“Strategies for Solution NMR Studies of Macromolecular Assemblies: Advancements in Solution NMR Techniques for Macromolecular Studies”, JASRAE, vol. 15, no. 9, pp. 274–278, Oct. 2018, Accessed: Jul. 08, 2024. [Online]. Available: https://ignited.in/jasrae/article/view/8845