Spectrophotometric Determination of Zn(II) in Pharmaceuticals Using (Di Amino di Hydroxy Pyrimidine) as Complexing Agent

A novel spectrophotometric method for the determination of Zn(II) in pharmaceuticals using a chelating agent

Abstract

Heterocyclic compound diamino and dihydroxy-pyramidine was blended and proposed as chelating specialist for the assurance of follow measures of zinc. Zinc(II) frames the age mangocolour complex with DADHP (Diaminodihydroxypyrimidine) in 13 stoichiometric proportion at pH-6 in acidic corrosive and sodium acetic acid derivation cushion within the sight of pyrideniumchloride as salting out specialist. The most extreme absorbance is seen at 480 nm. The Beer’s law is obeyed in the range of 1-6 µg. The molar absorptivity (ε) and Sandell’s sensitivity of the complex is 0.1484 x 104 L mol-1 cm-1 and 0.04545 µg cm-1 respectively. The method was successfully applied for the quantification of Zn (II) in pharmaceutical multi vitamin preparations in the presence of other trace elements. The statistical data evaluated reveals the sensitivity and accuracy of the method than the other methods reported.