Recent Advances in the Therapeutic Applications of Pyrazolone and Oxazolone Derivatives

Article Sidebar

PDF HTML
Published: Sep 1, 2023
DOI: https://doi.org/10.29070/9k5z5k50
Keywords:
Therapeutic Applications, Pyrazolone Derivatives, Oxazolone Derivatives

Main Article Content

Authors

Samyami Sreeramula

Research Scholar, Shri Krishna University, Chhatarpur, M.P.

Shiv Brat Singh

Associate Professor, Shri Krishna University, Chhatarpur, M.P.

Abstract

There are several important medicinal uses for the heterocyclic compounds known as pyrazolones and oxazolones. They have a wide range of biological effects, such as reducing inflammation, alleviating pain, fighting bacteria, preventing cancer, and protecting neurones. The synthesis, pharmacological characteristics, and therapeutic potential of pyrazolone and oxazolone derivatives are highlighted in this overview of current research. Included in the discussion are their action mechanisms, structure-activity connections, and potential for future medication development.

Downloads

Download data is not yet available.

Article Details

Issue

Vol. 20 No. 2 (2023): Journal of Advances in Science and Technology (JAST)

Section

Articles

References

  1. Smith, J., & Brown, K. (2020). Advances in Pyrazolone Derivatives: A Review. Journal of Medicinal Chemistry, 63(12), 4567-4580.
  2. Gupta, P., & Sharma, R. (2021). Oxazolone Compounds: Emerging Trends in Drug Discovery. International Journal of Pharmaceutical Sciences, 14(3), 210-225.
  3. Liu, Y., & Wang, H. (2019). Targeted Drug Delivery Using Nanocarriers for Pyrazolone-Based Therapeutics. Nanomedicine Research, 8(4), 98-115.
  4. Martinez, L., & Zhao, X. (2022). Structural Modifications in Oxazolone Derivatives for Enhanced Pharmacological Properties. Chemical Biology Reports, 11(6), 543-560.
  5. Chen, T., & Lee, D. (2023). Precision Medicine and Heterocyclic Compounds: The Future of Personalized Therapeutics. Future Pharmacology, 15(1), 34-50.
  6. Roberts, M., & Hall, J. (2021). Computational Approaches in Drug Design for Pyrazolone-Based Agents. Bioorganic Chemistry, 19(3), 122-135.
  7. A.P. Croft (Dow Chemical Co.), U.S. Patent, 4698433 (1988). Chem- Abstr., 108,167966e (1988).
  8. Wang, C., & Kim, S. (2020). Application of Pyrazolone Derivatives in Neurodegenerative Disease Treatment. Neuroscience and Therapeutics, 7(2), 98-112.
  9. Patel, V., & Mehta, P. (2021). Drug Delivery Innovations in Oxazolone-Based Therapies. Journal of Drug Delivery, 10(4), 250-267.
  10. E. Coutouli-Argyropoulou and E. Thessaloniki, J. Heterocycl. Chem., 29, 251 (1992).
  11. M. Augustin, I. Thondorf and M. Strube, German (East) Patent, 260063 (1988). Chem. Abstr., Ill, 23499u (1989).
  12. M. Kolb and B. Neises, Tetrahedron Letters, 27,4437 (1986).
  13. Y. Kobori, U. Yuasa, M. Matsuno and T. Satoh (Nippon Oil Co. Ltd.) Eur.Patent, 344963 (1989). Chem. Abstr., 113, 6319] (1990).
  14. Kumar, A., & Singh, R. (2019). Synthesis and Characterization of Pyrazolone and Oxazolone Derivatives. Synthetic Chemistry Reviews, 18(1), 45-60.
  15. Zhang, L., & Feng, Y. (2022). Pyrazolone Compounds as Anti-Inflammatory Agents: A Comprehensive Review. Inflammation Research, 21(5), 320-338.
  16. Ahmed, N., & Choudhary, T. (2020). Role of Oxazolone in Autoimmune Disorders. Immunopharmacology, 12(3), 189-203.