Antimicrobial Anticancer and Molecular Docking of Soil Bacterial Metabolites: Exploring the Role of Soil Bacterial Metabolites in Antimicrobial and Anticancer Activities

Abstract

Bacteria produce several secondary metabolites that they use as biocontrol agents. Inducingsystemic resistance (ISR) in host plants to a wide range of diseases andor abiotic stressors, competingfor an ecological niche or a substrate, and producing inhibitory allelochemicals are all well-establishedmechanisms by which PGPB mediate biocontrol. Both the aggressive colonisation of PGPBs and thedefensive maintenance of rhizosphere niches are promoted by the bacterial synthesis of allelochemicalssuch iron-chelating siderophores, antibiotics, biocidal volatiles, lytic enzymes, and detoxifying enzymes.