Magnetic Resonance Spectroscopy’s Use in the Diagnosis of Congenital and Developmental Brain Disorders: A comprehensive review of the applications and benefits of magnetic resonance spectroscopy in the diagnosis of congenital and developmental brain disorders

Abstract

In the study of brain development and in vivo metabolism, magnetic resonance spectroscopy (MRS) has shown to be a useful tool. Non-ionizing radiation is not used in MRS, which is a non-invasive method. White matter and metabolic issues, neurological ailments, and brain malignancies are just a few of the conditions that may be studied using MRS imaging to extract information about an infant's developing brain. Additionally, MRS provides quantitative information on particular metabolites, which can aid in illness diagnosis and therapy evaluation. This article focuses on the use of MRS in the diagnosis of congenital or developmental brain disorders. A brief explanation of the technical elements of MRS precedes the discussion of MRS diagnoses, which is followed by a review of normal brain spectroscopy in neonates changes with normal brain development.