Efficient Reaction Between Substituted 2-Acetyl-1-Naphthol/2-Acetyl-1-Naphthol and Different Substituted Benz Aldehydes: A Simple and Eco-Friendly Method for Chalcones Synthesis

Abstract

we have developed a simple,efficient and more eco-friendly method for synthesis of chalcones by grindingtechnique. The  notable  advantages of  present  method are  no  organic solvent  required  (except for  the  product recrystallization),  wasteminimization, simple operation, clean reaction profile, easy work-up, shorterreaction time (4-8 min.), high yields (84-95 %) and eco- friendly as comparedto conventional method.