Diaphragmatic, Pursed Lip, and 4-7-8 Breathing Techniques on Cancer-Related Fatigue- A Correlation & Regression Analysis on Age Groups, Gender, and Cancer Types
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Background and Objective: Cancer-related fatigue (CRF) is a prevalent and debilitating symptom among post-chemotherapy patients, impacting psychological well-being, autonomic regulation, and quality of life (QoL). This study evaluates the impact of diaphragmatic, pursed lip, and 4-7-8 breathing exercises on CRF, focusing on correlations across age, gender, and cancer types.
Methods: Post-chemotherapy patients were assigned to Diaphragmatic, Pursed Lip, 4-7-8 breathing, or control groups. Fatigue (BFI), psychological domains (PFS-R), and autonomic function (HRV metrics: SDNN and RMSSD) were assessed. Correlation matrices and regression analyses were used to explore relationships between breathing techniques and demographic factors.
Results: 4-7-8 breathing exhibited the strongest inverse correlation between fatigue and HRV (BFI vs SDNN, r = -0.40). Age (60–70 years) and males showed stronger fatigue reductions compared to other subgroups. Prostate cancer patients recorded the most notable improvement in fatigue and HRV metrics.
Conclusion: Breathing techniques, particularly 4-7-8 breathing, effectively reduce CRF and enhanced autonomic and psychological functioning, with variations across age, gender, and cancer type.
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- Bower, J. E. (2014). Cancer-related fatigue—mechanisms, risk factors, and treatments. Nature Reviews Clinical Oncology, 11(10), 597-609. https://doi.org/10.1038/nrclinonc.2014.127
- Brown, M., et al. (2021). Cancer type as a moderator of psychological interventions. Cancer, 127(12), 2101-2110.
- Chambers, S. K., Ferguson, M., & S. C. M. (2009). Psychological and quality of life outcomes of cancer care. Psycho-Oncology, 18(7), 719-728. https://doi.org/10.1002/pon.1482
- Fitch, M. I., & et al. (2009). Cancer and quality of life. In Oncology Nursing Society, Journal of Clinical Oncology, 27(24), 244-251.
- Minton, O., Richardson, A., & et al. (2008). Cancer-related fatigue and its treatment: A review of the literature. European Journal of Cancer Care, 17(6), 431-438. https://doi.org/10.1111/j.1365-2354.2008.00939.x
- Indian Council of Medical Research & National Institute of Medical Science. (2021). Annual report on cancer in India.
- ICMR Report. (2019). Cancer statistics report India.
- Johnson, L., et al. (2020). Time-course analysis of breathing exercises. Complementary Therapies in Medicine, 53, 102502.
- Jones, A., et al. (2019). Gender differences in autonomic regulation during breathing exercises. Autonomic Neuroscience, 220, 102558.
- Kabat-Zinn, J. (2003). Full catastrophe living: Using the wisdom of your body and mind to face stress, pain, and illness. Delta.
- Kinnunen, M., et al. (2010). Parasympathetic responses to slow breathing in men and women. Biological Psychology, 84(2), 183-189.
- Lehrer, P., et al. (2003). Behavioral interventions for autonomic regulation. Applied Psychophysiology and Biofeedback, 28(1), 1-20.
- McEwen, B. S. (2002). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338(3), 171-179.
- Nagaihte, et al. (2019). Cancer burden in North-East India. Asian Pacific Journal of Cancer Prevention, 20(6), 1635-1642.
- NCCN Guidelines. (2020). Cancer-related fatigue. National Comprehensive Cancer Network.
- Pennebaker, J. W. (2018). Opening up: The healing power of expressing emotions. Guilford Press.
- Prinja, et al. (2023). Financial toxicity of cancer care. BMJ Global Health, 8(2), e010322.
- Rao, et al. (2017). ICMR Cancer Registry Program Annual Report.
- Ramani, et al. (2023). Risk factors for cancer in India. Current Oncology Reports, 25(2), 45-54.
- Ream, E., & Richardson, A. (2000). Fatigue in patients with cancer: A review. Journal of Clinical Nursing, 9(4), 493-500. https://doi.org/10.1046/j.1365-2702.2000.00439.x
- Sampath, S., & et al. (2017). The role of controlled breathing in autonomic nervous system regulation in cancer patients. Journal of Psychosomatic Research, 93, 54-61. https://doi.org/10.1016/j.jpsychores.2017.08.009
- Seeman, T. E., et al. (2001). Age-related differences in autonomic function. Psychosomatic Medicine, 63(5), 783-790.
- Shanker, R., et al. (2021). Cancer incidence in NE India. Journal of Global Oncology, 7, 123-134.
- Sharma, et al. (2020). Viral hepatitis and liver cancer. Indian Journal of Medical Research, 151(3), 243-252.
- Smith, A. J., et al. (2020). The role of HRV in stress and fatigue management. Journal of Behavioral Medicine, 43(1), 10-25.
- Smith, & Mallath. (2019). Cancer burden in India: Historical perspectives. Lancet Oncology, 20(2), e71-e78.
- Sathish Kumar, et al. (2022). Cancer incidence estimates for 2022 & projection for 2025. ICMR.
- Servaes, P., et al. (2002). Fatigue in cancer patients. Journal of Pain and Symptom Management, 23(6), 432-442.