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Authors

D. J. Tanigaiselvane

Dr. Ravi Shankar Ravi

Dr. Anil Kumar Singh

Abstract

Background and Objective: Cancer-related fatigue (CRF) is a prevalent and debilitating symptom among post-chemotherapy patients, impacting psychological well-being, autonomic regulation, and quality of life (QoL). This study evaluates the impact of diaphragmatic, pursed lip, and 4-7-8 breathing exercises on CRF, focusing on correlations across age, gender, and cancer types.


Methods: Post-chemotherapy patients were assigned to Diaphragmatic, Pursed Lip, 4-7-8 breathing, or control groups. Fatigue (BFI), psychological domains (PFS-R), and autonomic function (HRV metrics: SDNN and RMSSD) were assessed. Correlation matrices and regression analyses were used to explore relationships between breathing techniques and demographic factors.


Results: 4-7-8 breathing exhibited the strongest inverse correlation between fatigue and HRV (BFI vs SDNN, r = -0.40). Age (60–70 years) and males showed stronger fatigue reductions compared to other subgroups. Prostate cancer patients recorded the most notable improvement in fatigue and HRV metrics.


Conclusion: Breathing techniques, particularly 4-7-8 breathing, effectively reduce CRF and enhanced autonomic and psychological functioning, with variations across age, gender, and cancer type.

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