Impact of Mushroom Consumption on Diabetic Type 2 Patients

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Published: Apr 1, 2024
DOI: https://doi.org/10.29070/6th22747
Keywords:
mushroom consumption, diabetic type 2 patients, patients

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Authors

Bedor Khalid Al Soliman

Senior Ultrasonographer, Prince Sultan Military Medical City, Riyadh

Reem M. Al Zahem

Clinical Nutrition Specialist, Prince Sultan Military Medical City, Riyadh

Turki Z. Al Mutairi

Health Informatics Technician, Prince Sultan Military Medical City, Riyadh

Abstract

The complicated disease known as diabetes mellitus is caused by the body producing insufficient amounts of insulin to regulate blood glucose levels. This illness poses a global health risk and calls for inexpensive, non-adverse medication. Many synthetic hypoglycemia diabetes medicines are ineffective due to side effects. This has caused studies to focus more on medicinal plants and herbs, which are thought to be relatively harmless. There is a kind of phytotherapy that includes edible mushrooms that may be used to treat diabetes. They are abundant in naturally occurring substances such fibers, polysaccharides, phenolics, and alkaloids and have long been recognized for their ability to have antihyperlipidemic, antioxidant, and antidiabetic properties. Dietary supplements and functional foods derived from mushrooms can help treat pre-existing problems and postpone the start of potentially fatal diseases. This is confined to the suppression of intestinal glucosidase and the breakdown of composite polysaccharides by pancreatic amylase, which helps prevent and effectively cure type 2 diabetes. Additionally, the carbohydrates included in mushrooms function as prebiotics and alter the makeup of gut bacteria, which can lower insulin resistance. This paper explores the phathophysiology and complication of diabetes and provides details on the potential antidiabetic properties of several mushroom species. Nevertheless, more investigation is required to completely comprehend the therapeutic applications of mushrooms. Pre-clinical and clinical research, tests for enzyme inhibition, human trials, pilot studies, prospective and retrospective studies, and human trials should all be included in this research.

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Vol. 19 No. 2 (2024): International Journal of Physical Education and Sports Sciences (IJOPESS)

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References

  1. Al-Shoumer KA, Al-Essa TM. Is there a relationship between vitamin D with insulin resistance and diabetes mellitus?. World journal of diabetes. 2015 Jul 7;6(8):1057.
  2. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes care. 2010 Jan 1;33(Supplement_1):S62-9.
  3. Arunachalam K, Sreeja PS, Yang X. The antioxidant properties of mushroom polysaccharides can potentially mitigate oxidative stress, beta-cell dysfunction and insulin resistance. Frontiers in Pharmacology. 2022 May 5;13:874474.
  4. Aramabašic Jovanovic J, Mihailovic M, Uskokovic A, Grdovic N, Dinic S, Vidakovic M. The Effects of Major Mushroom Bioactive Compounds on Mechanisms That Control Blood Glucose Level. J. Fungi 2021, 7, 58.
  5. Asrafuzzaman M, Rahman MM, Mandal M, Marjuque M, Bhowmik A, Rokeya B, Hassan Z, Faruque MO. Oyster mushroom functions as an anti-hyperglycaemic through phosphorylation of AMPK and increased expression of GLUT4 in type 2 diabetic model rats. Journal of Taibah University medical sciences. 2018 Oct 1;13(5):465-71.
  6. Bauer Petrovska B. Protein fraction in edible Macedonian mushrooms. European Food Research and Technology. 2001 Mar;212:469-72.
  7. Batbayar S, Lee DH, Kim HW. Immunomodulation of fungal β-glucan in host defense signaling by dectin-1. Biomolecules & therapeutics. 2012 Sep;20(5):433.
  8. Cardwell G, Bornman JF, James AP, Black LJ. A review of mushrooms as a potential source of dietary vitamin D. Nutrients. 2018 Oct 13;10(10):1498.
  9. Centers for Disease Control and Prevention. National Diabetes Fact Sheet: General Information and National Estimates on Diabetes in the United States, 2005. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2005. Available at: http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2005.pdf Accessed May 29, 2008.
  10. Cui B, Han L, Qu J, Lv Y. Hypoglycemic activity of Grifola frondosa rich in vanadium. Biological trace element research. 2009 Nov;131:186-91.
  11. Chaturvedi VK, Dubey SK, Singh MP. Antidiabetic potential of medicinal mushrooms. InPhytochemicals from medicinal plants 2019 Nov 15 (pp. 137-158). Apple Academic Press
  12. Du B, Zhu F, Xu B. An insight into the anti-inflammatory properties of edible and medicinal mushrooms. Journal of Functional Foods. 2018 Aug 1;47:334-42.
  13. Dubey SK, Chaturvedi VK, Mishra D, Bajpeyee A, Tiwari A, Singh MP. Role of edible mushroom as a potent therapeutics for the diabetes and obesity. 3 Biotech. 2019 Dec;9:1-2.
  14. Ekowati N, Yuniati NI, Hernayanti H, Ratnaningtyas NI. Antidiabetic potentials of button mushroom (Agaricus bisporus) on alloxan-induced diabetic rats. Biosaintifika: Journal of Biology & Biology Education. 2018 Dec 31;10(3):655-62.
  15. Feeney MJ, Dwyer J, Hasler-Lewis CM, Milner JA, Noakes M, Rowe S, Wach M, Beelman RB, Caldwell J, Cantorna MT, Castlebury LA. Mushrooms and health summit proceedings. The Journal of nutrition. 2014 Jul 1;144(7):1128S-36S.
  16. Guo WL, Shi FF, Li L, Xu JX, Chen M, Wu L, Hong JL, Qian M, Bai WD, Liu B, Zhang YY. Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice. International journal of biological macromolecules. 2019 Jun 15;131:81-8.
  17. Huan G., Cai W., Xu B. Vitamin D2, ergosterol, and vitamin B2 content in commercially dried mushrooms marketed in China and increased vitamin D2 content following UV-C irradiation. Int. J. Vitam. Nutr. Res. 2016;21:1–10.]
  18. Harding JL, Pavkov ME, Magliano DJ, Shaw JE, Gregg EW. Global trends in diabetes complications: a review of current evidence. Diabetologia. 2019 Jan;62:3-16.
  19. Han NS, Ahmad WA, Ishak WW. Quality characteristics of Pleurotus sajor-caju powder: Study on nutritional compositions, functional properties and storage stability. Sains Malays. 2016 Nov 1;45(11):1617-23.
  20. Idf Diabetes Atlas. 9th ed. International Diabetes Federation; Brussels, Belgium: 2019.
  21. Islam T, Yu X, Xu B. Phenolic profiles, antioxidant capacities and metal chelating ability of edible mushrooms commonly consumed in China. LWT-Food Science and Technology. 2016 Oct 1;72:423-31.
  22. Jovanović JA, Mihailović M, Uskoković AS, Grdović N, Dinić S, Poznanović G, Mujić I, Vidaković M. Evaluation of the antioxidant and antiglycation effects of Lactarius deterrimus and Castanea sativa extracts on hepatorenal injury in streptozotocin-induced diabetic rats. Frontiers in Pharmacology. 2017 Oct 31;8:793.
  23. Kaur A, Dhingra GS, Shri R. Antidiabetic potential of mushrooms. Asian J Pharm Res. 2015;5(2):111-25.
  24. Kou L, Du M, Liu P, Zhang B, Zhang Y, Yang P, Shang M, Wang X. Anti-diabetic and anti-nephritic activities of Grifola frondosa mycelium polysaccharides in diet-streptozotocin-induced diabetic rats via modulation on oxidative stress. Applied biochemistry and biotechnology. 2019 Jan 15;187:310-22.
  25. Kolundzic MD, Grozdanic NO, Stanojkovic TP, Milenkovic MT, Dinic MR, Golic NE, Kojic M, Kundakovic TD. Antimicrobial and cytotoxic activities of the sulphur shelf medicinal mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia. International Journal of Medicinal Mushrooms. 2016;18(6).
  26. Lia WL, Zhengc HC, Bukurub J, De Kimpeb N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Natural medicines used in the traditional Chinese medical system for therapy of diabetesmellitus," Journal of Ethnopharmacology. 2004 May;92(1):1-21.
  27. Lo HC, Wasser SP. Medicinal mushrooms for glycemic control in diabetes mellitus: history, current status, future perspectives, and unsolved problems. International journal of medicinal mushrooms. 2011;13(5).
  28. Lu X, Brennan MA, Narciso J, Guan W, Zhang J, Yuan L, Serventi L, Brennan CS. Correlations between the phenolic and fibre composition of mushrooms and the glycaemic and textural characteristics of mushroom enriched extruded products. Lwt. 2020 Jan 1;118:108730.
  29. Lin X, Brennan-Speranza TC, Levinger I, Yeap BB. Undercarboxylated osteocalcin: experimental and human evidence for a role in glucose homeostasis and muscle regulation of insulin sensitivity. Nutrients. 2018 Jun 29;10(7):847.
  30. Ma X, Yang M, He Y, Zhai C, Li C. A review on the production, structure, bioactivities and applications of Tremella polysaccharides. International journal of immunopathology and pharmacology. 2021 Apr;35:20587384211000541.
  31. Mahapatra S, Banerjee D. Fungal exopolysaccharide: production, composition and applications. Microbiology insights. 2013 Jan;6:MBI-S10957.
  32. Patel DK, Dutta SD, Ganguly K, Cho SJ, Lim KT. Mushroom-derived bioactive molecules as immunotherapeutic agents: A review. Molecules. 2021 Mar 4;26(5):1359.
  33. Panigrahy SK, Bhatt R, Kumar A. Targeting type II diabetes with plant terpenes: the new and promising antidiabetic therapeutics. Biologia. 2021 Jan;76(1):241-54.
  34. Passari AK, Sánchez S, editors. An introduction to mushroom. BoD–Books on Demand; 2020 Jul 1.
  35. Robbins RJ. Phenolic acids in foods: an overview of analytical methodology. Journal of agricultural and food chemistry. 2003 May 7;51(10):2866-87.
  36. Sung CC, Liao MT, Lu KC, Wu CC. Role of vitamin D in insulin resistance. BioMed Research International. 2012;2012(1):634195
  37. Singh MP, Rai SN, Dubey SK, Pandey AT, Tabassum N, Chaturvedi VK, Singh NB. Biomolecules of mushroom: A recipe of human wellness. Critical Reviews in Biotechnology. 2022 Aug 18;42(6):913-30.
  38. Schmeltz L, Metzger B. Diabetes/syndrome X. InComprehensive medicinal chemistry II 2006 Nov (pp. 417-458). Elsevier Ltd.
  39. Sari M, Prange A, Lelley JI, Hambitzer R. Screening of beta-glucan contents in commercially cultivated and wild growing mushrooms. Food Chemistry. 2017 Feb 1;216:45-51.
  40. Unger RH, Orci L. Paracrinology of islets and the paracrinopathy of diabetes. Proceedings of the national academy of Sciences. 2010 Sep 14;107(37):16009-12.
  41. Urbain P, Singler F, Ihorst G, Biesalski HK, Bertz H. Bioavailability of vitamin D2 from UV-B-irradiated button mushrooms in healthy adults deficient in serum 25-hydroxyvitamin D: A randomized controlled trial. European journal of clinical nutrition. 2011 Aug;65(8):965-71.
  42. Valverde ME, Hernández-Pérez T, Paredes-López O. Edible mushrooms: improving human health and promoting quality life. International journal of microbiology. 2015;2015(1):376387.
  43. Wagner R, Mitchell DA, Sassaki GL, de Almeida Amazonas MA. Links between morphology and physiology of Ganoderma lucidum in submerged culture for the production of exopolysaccharide. Journal of Biotechnology. 2004 Oct 19;114(1-2):153-64.
  44. Xiao Y, Chen L, Fan Y, Yan P, Li S, Zhou X. The effect of boletus polysaccharides on diabetic hepatopathy in rats. Chemico-Biological Interactions. 2019 Aug 1;308:61-9.
  45. Zhong JJ, Bai FW, Zhang W, editors. Biotechnology in China I: from bioreaction to bioseparation and bioremediation. Springer Science & Business Media; 2009 Oct 8.
  46. Zhong JJ, editor. Biomanufacturing. Springer Science & Business Media; 2004 May 3.
  47. Zhang WX, Zhong JJ. Effect of oxygen concentration in gas phase on sporulation and individual ganoderic acids accumulation in liquid static culture of Ganoderma lucidum. Journal of bioscience and bioengineering. 2010 Jan 1;109(1):37-40.
  48. Zhang L, Hu Y, Duan X, Tang T, Shen Y, Hu B, Liu A, Chen H, Li C, Liu Y. Characterization and antioxidant activities of polysaccharides from thirteen boletus mushrooms. International journal of biological macromolecules. 2018 Jul 1;113:1-7.
  49. Zhang C, Li J, Hu C, Wang J, Zhang J, Ren Z, Song X, Jia L. Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from Hericium erinaceus SG-02 in streptozotocin-induced diabetic mice. Scientific Reports. 2017 Sep 7;7(1):10847.