Antimicrobial Properties of Syzygium Aromaticum Extract Against Common Uropathogenic Bacteria
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Urinary tract infections (UTIs) cause a large burden of disease affecting 150-250 million people per year worldwide the study involved 400 urine samples from patients suspected of having UTIs who visited tertiary-care hospitals, private hospitals, and pathology centers in Rewa District from October 2021 to September 2023. Antibiotic resistance is a pressing issue, necessitating new treatments against MDR microorganisms. Essential oils, being multi-component, may offer new options to combat microbial resistance, potentially outperforming conventional antimicrobials that target a single site, particularly in E. coli.
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- Wolfe, A.J.; Brubaker, L. “Sterile Urine” and the Presence of Bacteria. Eur. Urol. 2015, 68, 173–174.
- McCann, E.; Sung, A.H.; Ye, G.; Vankeepuram, L.; Tabak, Y.P. Contributing Factors to the Clinical and Economic Burden of Patients with Laboratory-Confirmed Carbapenem-Nonsusceptible Gram-Negative Urinary Tract Infections. Clin. Outcomes Res. CEOR 2020, 12, 191–200.
- Huang, L.; Huang, C.; Yan, Y.; Sun, L.; Li, H. Urinary Tract Infection Etiological Profiles and Antibiotic Resistance Patterns Varied Among Different Age Categories: A Retrospective Study from a Tertiary General Hospital During a 12-Year Period. Front. Microbiol. 2021, 12, 813145.
- van Buul, L.W.; Vreeken, H.L.; Bradley, S.F.; Crnich, C.J.; Drinka, P.J.; Geerlings, S.E.; Jump, R.L.P.; Mody, L.; Mylotte, J.J.; Loeb, M.; et al. The Development of a Decision Tool for the Empiric Treatment of Suspected Urinary Tract Infection in Frail Older Adults: A Delphi Consensus Procedure. J. Am. Med. Dir. Assoc. 2018, 19, 757–764.
- Gomila, A.; Shaw, E.; Carratala, J.; Leibovici, L.; Tebe, C.; Wiegand, I.; Vallejo- Torres, L.; Vigo, J.M.; Morris, S.; Stoddart, M.; et al. Predictive factors for multidrug- resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections. Antimicrob. Resist. Infect. Control 2018, 7, 111.
- Nicolle, L.E. Complicated urinary tract infection in adults. Can. J. Infect. Dis. Med. Microbiol. 2005, 16, 349–360.
- Rando, E.; Giovannenze, F.; Murri, R.; Sacco, E. A review of recent advances in the treatment of adults with complicated urinary tract infection. Expert Rev. Clin. Pharmacol. 2022, 15, 1053–1066.
- Abraham, S.N.; Miao, Y. The nature of immune responses to urinary tract infections.
- Nat. Rev. Immunol. 2015, 15, 655–663.
- Li, L.; Li, Y.; Yang, J.; Xie, X.; Chen, H. The immune responses to different Uropathogens call individual interventions for bladder infection. Front. Immunol. 2022, 13, 953354.
- Govindarajan, D.K.; Kandaswamy, K. Virulence factors of uropathogens and their role in host pathogen interactions. Cell Surf. 2022, 8, 100075.
- Shrestha, L.B.; Baral, R.; Khanal, B. Comparative study of antimicrobial resistance and biofilm formation among Gram-positive uropathogens isolated from community- acquired urinary tract infections and catheter-associated urinary tract infections. Infect. Drug Resist. 2019, 12, 957–963.
- Jacobsen, S.M.; Shirtliff, M.E. Proteus mirabilis biofilms and catheter-associated urinary tract infections. Virulence 2011, 2, 460–465.
- Amankwah, S.; Abdella, K.; Kassa, T. Bacterial Biofilm Destruction: A Focused Review on The Recent Use of Phage-Based Strategies with Other Antibiofilm Agents. Nanotechnol. Sci. Appl. 2021, 14, 161–177.
- van Buul, L.W.; Vreeken, H.L.; Bradley, S.F.; Crnich, C.J.; Drinka, P.J.; Geerlings, S.E.; Jump, R.L.P.; Mody, L.; Mylotte, J.J.; Loeb, M.; et al. The Development of a Decision Tool for the Empiric Treatment of Suspected Urinary Tract Infection in Frail Older Adults: A Delphi Consensus Procedure. J. Am. Med. Dir. Assoc. 2018, 19, 757–764.