Main Article Content

Authors

Neetu Parmar

Dr. Amit Tiwari

Dr. Arjun Singh Parmar

Abstract

Urinary tract infections (UTIs) cause a large burden of disease affecting 150-250 million people per year worldwide the study involved 400 urine samples from patients suspected of having UTIs who visited tertiary-care hospitals, private hospitals, and pathology centers in Rewa District from October 2021 to September 2023. Antibiotic resistance is a pressing issue, necessitating new treatments against MDR microorganisms. Essential oils, being multi-component, may offer new options to combat microbial resistance, potentially outperforming conventional antimicrobials that target a single site, particularly in E. coli.

Downloads

Download data is not yet available.

Article Details

Section

Articles

References

  1. Wolfe, A.J.; Brubaker, L. “Sterile Urine” and the Presence of Bacteria. Eur. Urol. 2015, 68, 173–174.
  2. McCann, E.; Sung, A.H.; Ye, G.; Vankeepuram, L.; Tabak, Y.P. Contributing Factors to the Clinical and Economic Burden of Patients with Laboratory-Confirmed Carbapenem-Nonsusceptible Gram-Negative Urinary Tract Infections. Clin. Outcomes Res. CEOR 2020, 12, 191–200.
  3. Huang, L.; Huang, C.; Yan, Y.; Sun, L.; Li, H. Urinary Tract Infection Etiological Profiles and Antibiotic Resistance Patterns Varied Among Different Age Categories: A Retrospective Study from a Tertiary General Hospital During a 12-Year Period. Front. Microbiol. 2021, 12, 813145.
  4. van Buul, L.W.; Vreeken, H.L.; Bradley, S.F.; Crnich, C.J.; Drinka, P.J.; Geerlings, S.E.; Jump, R.L.P.; Mody, L.; Mylotte, J.J.; Loeb, M.; et al. The Development of a Decision Tool for the Empiric Treatment of Suspected Urinary Tract Infection in Frail Older Adults: A Delphi Consensus Procedure. J. Am. Med. Dir. Assoc. 2018, 19, 757–764.
  5. Gomila, A.; Shaw, E.; Carratala, J.; Leibovici, L.; Tebe, C.; Wiegand, I.; Vallejo- Torres, L.; Vigo, J.M.; Morris, S.; Stoddart, M.; et al. Predictive factors for multidrug- resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections. Antimicrob. Resist. Infect. Control 2018, 7, 111.
  6. Nicolle, L.E. Complicated urinary tract infection in adults. Can. J. Infect. Dis. Med. Microbiol. 2005, 16, 349–360.
  7. Rando, E.; Giovannenze, F.; Murri, R.; Sacco, E. A review of recent advances in the treatment of adults with complicated urinary tract infection. Expert Rev. Clin. Pharmacol. 2022, 15, 1053–1066.
  8. Abraham, S.N.; Miao, Y. The nature of immune responses to urinary tract infections.
  9. Nat. Rev. Immunol. 2015, 15, 655–663.
  10. Li, L.; Li, Y.; Yang, J.; Xie, X.; Chen, H. The immune responses to different Uropathogens call individual interventions for bladder infection. Front. Immunol. 2022, 13, 953354.
  11. Govindarajan, D.K.; Kandaswamy, K. Virulence factors of uropathogens and their role in host pathogen interactions. Cell Surf. 2022, 8, 100075.
  12. Shrestha, L.B.; Baral, R.; Khanal, B. Comparative study of antimicrobial resistance and biofilm formation among Gram-positive uropathogens isolated from community- acquired urinary tract infections and catheter-associated urinary tract infections. Infect. Drug Resist. 2019, 12, 957–963.
  13. Jacobsen, S.M.; Shirtliff, M.E. Proteus mirabilis biofilms and catheter-associated urinary tract infections. Virulence 2011, 2, 460–465.
  14. Amankwah, S.; Abdella, K.; Kassa, T. Bacterial Biofilm Destruction: A Focused Review on The Recent Use of Phage-Based Strategies with Other Antibiofilm Agents. Nanotechnol. Sci. Appl. 2021, 14, 161–177.
  15. van Buul, L.W.; Vreeken, H.L.; Bradley, S.F.; Crnich, C.J.; Drinka, P.J.; Geerlings, S.E.; Jump, R.L.P.; Mody, L.; Mylotte, J.J.; Loeb, M.; et al. The Development of a Decision Tool for the Empiric Treatment of Suspected Urinary Tract Infection in Frail Older Adults: A Delphi Consensus Procedure. J. Am. Med. Dir. Assoc. 2018, 19, 757–764.